Found 11 matching trials
AZD5305 hADME in Patients With Advanced Solid Malignancies PHASE1 This Phase I, open-label study aims to study to absolute bioavailability of...
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Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors PHASE1 This research is designed to determine if experimental treatment with Antib...
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Targeted Pathway Inhibition in Patients With Pancreatic Cancer EARLY_PHASE1 This early phase I trial aims to determine how cobimetinib, olaparib, onvan...
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OHSU Knight Cancer Institute
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Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician's Choice New Hormonal Agents PHASE3 The intention of the study is to demonstrate superiority of Saruparib (AZD5...
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Active Not Recruiting
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A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies PHASE1 This research study is studying a new compound, AZD8205, as a possible trea...
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A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation PHASE3 The purpose of the study is to demonstrate superiority of Saruparib (AZD530...
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Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05) PHASE3 The primary objective of this study is to measure efficacy of saruparib + p...
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A Trial to Learn How Safe AZD9750 is and How Well it Works in People With Metastatic Prostate Cancer When Given With or Without Other Anticancer Drugs PHASE1 ANDROMEDA is a first-in-human, Phase I/II, open-label, multicenter study of...
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A Study to Investigate the Biological Effects of Saruparib (AZD5305), Darolutamide, and in Combination in Men With Newly Diagnosed Prostate Cancer. PHASE1 A Study to Investigate the Biological Effects of Saruparib (AZD5305) Alone,...
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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study PHASE2 This phase II trial tests how well biomarker tests on patients tumor tissue...
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Loma Linda University Medical Center
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